Depression affects over 40% of Australians at some point in their lives, and finding effective treatment options can feel overwhelming. While traditional approaches like therapy and medication remain important, many people are now considering complementary therapies that address mental health from a different angle.
Hyperbaric oxygen therapy (HBOT) is showing promise as a natural approach that may help with depression treatment by targeting the brain’s fundamental needs.
Hyperbaric oxygen therapy is not a standalone treatment for depression and should not replace professional mental health care. It is intended as a complementary wellness therapy and may not be suitable for everyone.
What Is Hyperbaric Oxygen Therapy?
Hyperbaric oxygen therapy involves breathing pure oxygen in a pressurised chamber, typically at 1.35 atmospheric pressure. This process allows your body to absorb significantly more oxygen than normal breathing, saturating your blood plasma and reaching every cell in your body, including those in your brain.
At Folium Health, our Hyperbaric oxygen therapy in Sydney is designed to deliver controlled, safe oxygen therapy. Each session lasts between 60 to 90 minutes, during which you can relax, meditate, read, or even rest while your body absorbs the therapeutic benefits.
How HBOT May Support Depression Treatment
Research suggests that hyperbaric oxygen therapy could help with depression symptoms through several mechanisms. Understanding these pathways helps explain why HBOT is gaining attention in the mental health space.
In our clinical experience at Folium Health, clients using HBOT alongside counselling, lifestyle changes, and medical care often report improvements in mental clarity, energy levels, and emotional resilience over time. Individual results vary, and outcomes depend on consistency and overall treatment approach.
Enhanced Brain Oxygenation
Depression often correlates with reduced blood flow and oxygen delivery to certain brain regions. HBOT floods the brain with oxygen, potentially improving cellular function in areas responsible for mood regulation and emotional processing.
Reduced Inflammation
Chronic inflammation is increasingly recognised as a contributor to depression. Studies have shown that HBOT has powerful anti-inflammatory properties, which may help ease symptoms like fatigue, brain fog, and low mood that often accompany depression.
Neurotransmitter Support
HBOT may influence the production and function of neurotransmitters like serotonin and dopamine, the brain chemicals responsible for feelings of wellbeing and happiness. By helping balance neurotransmitters, oxygen therapy could contribute to improved mood stability.
Neuroplasticity Promotion
One of the most exciting aspects of HBOT is its potential to promote neuroplasticity, the brain’s ability to form new neural connections and heal. This increased oxygen supply may stimulate the growth of new brain cells and strengthen existing pathways, helping with better emotional regulation and cognitive function.

The Science Behind HBOT and Mental Health
While research into HBOT for depression is still developing, the existing evidence is promising. Peer-reviewed studies have shown that increased oxygen availability may improve cerebral blood flow, cognitive performance, and markers associated with anxiety and mood regulation, supporting overall brain health.
HBOT should be viewed as a complementary therapy rather than a replacement for conventional depression treatment. The best outcomes often occur when oxygen therapy is combined with established approaches such as counselling, lifestyle modifications, and medical treatment when appropriate.
At Folium Health, we take an evidence-based approach to wellness, ensuring that HBOT is integrated thoughtfully into your health strategy.
What to Expect at Folium Health
Your journey with hyperbaric oxygen therapy at Folium Health begins with a thorough consultation. Our experienced practitioners, trained in hyperbaric oxygen therapy and integrative wellness care, will discuss your health history, mental health goals, current treatments, and any concerns you may have. We’ll assess your individual needs to create a personalised treatment plan that’s both safe and effective.
Before each session, you’ll be guided on what to expect and given comfortable clothing to wear.
During the session, you’ll relax inside our advanced hyperbaric chamber while breathing pure oxygen through a mask. The pressure increase feels similar to flying in an aeroplane, gentle and gradual.
After your session, there’s no downtime. You can immediately return to your daily activities. We’ll work with you to determine the best frequency and duration of sessions based on your goals and response to treatment.
Is HBOT Right for You?
Hyperbaric oxygen therapy may be worth considering if you’re experiencing depression and are interested in natural, complementary approaches to mental health. It’s particularly appealing for those who want to support their brain health alongside traditional treatments.
HBOT isn’t suitable for everyone. Certain medical conditions may require additional consideration, which is why we conduct thorough consultations before beginning treatment.
If you’re already working with a mental health professional, we encourage you to discuss HBOT as part of your comprehensive treatment plan. Our team at Folium Health is happy to work with your existing healthcare providers to ensure integrated care.

Ready to Begin Your Journey?
Ready to see how hyperbaric oxygen therapy could support your mental health journey? Book a consultation with Folium Health today and discover what advanced oxygen therapy can do for your wellbeing.